Around 4:40am, a gold 2001 model Toyota Camry was travelling west on Old Yanchep Road when the driver failed to negotiate a left hand bend and lost control of the vehicle.
The Toyota left the road and hit a tree then a wire fence, trapping the driver in the vehicle.
The 46 year old male driver of the car received serious injuries in the crash and was conveyed to Royal Perth Hospital, where he remains in the Intensive Care Unit.
Police would like to speak to anyone who witnessed this crash, or saw the Toyota Camry prior to the crash. Anyone with information is asked to call Crime Stoppers on 1800 333 000 or to make a report online at www.crimestopperswa.com.au